How does caffeine in coffee lower cholesterol?

Caffeine reduces the production of LDL cholesterol by affecting two proteins. Photo: File

Many benefits of coffee have been reported and more are emerging. Now experts have discovered the scientific reason for the unhealthy caffeine in coffee and other beverages, which lowers LDL cholesterol.

Scientists at McMaster University say that excessive consumption of caffeine reduces the amount of a type of protein in the blood called ‘PCSK-9’.

 This protein enters the liver and prevents it from eliminating bad LDL cholesterol. This does not increase the cholesterol which would otherwise accumulate in the arteries and lead to heart attack and stroke.

Senior scientist Dr. Richard Austin, who was involved in the research, said that another function of caffeine is to inhibit the activity of another protein called SREBP2 and this protein further reduces the production of PCSK-9. That is, caffeine prevents the formation of LDL in two ways.


In addition, SREPB2 protein directly and indirectly promotes a variety of diseases, including diabetes and fatty liver. But scientists warn that simply drinking coffee does not help. If you are mixing sugar and cream in it, then all the benefits can be lost. This minimizes the effectiveness of caffeine. Then the habit of soft drinks and sweet syrup makes everyone water.


However, excessive amounts of caffeine can be harmful to the body and that is why coffee consumption should be kept normal but it is possible to take a closer look at caffeine and take note of its active ingredients. You will be able to make an effective medicine by mixing them in a supplement. This drug will play an important role in lowering cholesterol worldwide.

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Author: DoctorMaryam.org

4th Professional Medical Student. Karachi Medical and Dental College.

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