The scientific cause of insomnia in old age has come to light

According to preliminary research, the hypothalamus, the brainstem, increases the production of proteins called hypocretin and neurotransmitters, which wake up the elderly and make them accustomed to insomnia.
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We know that the sleep of the elderly decreases with age. Explaining the scientific reason for this, experts have said that in old age, the brain cells (nerves) that wake us up become abnormally active.

This explains why the sleep of the elderly is affected so much. According to scientists, 50% of men over the age of 65 complain of insomnia and lack of sleep.

According to Louis de Licia, a professor at Stanford University, 80% of the elderly suffer from severe insomnia if they have Alzheimer’s or other mental illnesses. It should be noted that lack of sleep also gives rise to many more mental disorders.

In the laboratory, neurons were observed in the brains of young and old mice, which were emanating from a well-known site called the hypothalamus to form a protein called ‘hypocretin’. These proteins play an important role in awakening or retaining human beings and do the same in mice.

At first, it was thought that the brain’s internal electrical system, or circuit, might cause some kind of bad sleep because we know that with age, 80 percent of hypochlorites are reduced. But the real reason turned out to be that the rate of fire or activity of hypocretin increases in older rats. This is because they cause wakefulness and thus older people stay awake with more protein activity instead of lack of sleep.

Although mouse models do not equate to humans, they can be interpreted in some way. Older people are more likely to be bedridden and sleep deprived due to excessive hypocritic activity.

However, Renata Reha, a sleep and brain specialist at the University of Edinburgh, described the study as “very important” and said it was a solution to the mystery. However, according to Professor Lewis, this is only half the answer to our question and now we will see what is the sleep stimulus system in the elderly and how it works.



4th Professional Medical Student. Karachi Medical and Dental College.

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