You can lose up to 15% of your starting body weight when using semaglutide in injections for weight loss (such as Ozempic). From 0.25 mg at the beginning to 2.4 mg once a week by week 16, the semaglutide dosage is gradually increased. In order to answer the question “how much weight can you lose with semaglutide,” researchers at the University of Liverpool created a study with very specific guidelines.
A group of 1961 adults was gathered who had a BMI that indicated obesity (>30). The average weight loss in those who received the semaglutide slimming injection was nearly 15% (as opposed to the placebo’s -2.4%). You can shed about 15 kg in 68 weeks by taking Ozempic or another medication along with semaglutide once per week (17 months).
Here are the precise weight loss results and advancements made by a group of almost 2,000 participants in a study released in 2021. Two research subgroups were created from the participant pool.
The first received a weekly slimming injection with semaglutide (the same substance found in, for example, Ozempic) starting at a dose of 0.25 mg to 2.4 mg, and received recommendations on how to lose weight through lifestyle changes.
- The first received a weekly slimming injection with semaglutide (the same substance found in, for example, Ozempic) starting at a dose of 0.25 mg to 2.4 mg, and received recommendations on how to lose weight through lifestyle changes.
- The second group of people received only recommendations regarding lifestyle changes for effective weight loss.
Weight loss with semaglutide slimming injections (e.g. Ozempic) progressed as follows:
- 1st month (4 weeks) of slimming injections – approx. -2.5% of the initial body weight (a person weighing 100 kg loses 2.5 kg);
- 2nd month (8 weeks) of slimming injections – approx. -4% of the initial body weight (a person weighing 100 kg loses approx. 4 kg);
- 3rd month (12 weeks) of slimming injections – approx. -6% of the initial body weight (a person weighing 100 kg loses approx. 6 kg);
- 4th month (16 weeks) of slimming injections – approx. -8% of the initial body weight (a person weighing 100 kg loses approx. 8 kg);
- 5th month (20 weeks) of slimming injections – approx. -9.5% of the initial body weight (a person weighing 100 kg loses approx. 9.5 kg);
After the fifth month of taking slimming injections, you can still lose weight effectively, but the pace of weight loss is noticeably slowing down:
- 7th month (28 weeks) of slimming injections – approx. -11.5% of the initial body weight (a person weighing 100 kg loses approx. 11.5 kg);
- 9th month (36 weeks) of slimming injections – approx. -13% of the initial body weight (a person weighing 100 kg loses approx. 13 kg);
- 11th month (44 weeks) of slimming injections – approx. -14.8% of the initial body weight (a person weighing 100 kg loses approx. 14.8 kg);
- 13th month (52 weeks) of slimming injections – approx. -15.8% of the initial body weight (a person weighing 100 kg loses approx. 15.8 kg);
- 15th month (60 weeks) of slimming injections – approx. 14.9% of the initial body weight (a person weighing 100 kg loses approx. 14.9 kg).
But more than just the average weight loss is remarkable. Even more amazing is the difference in the number of people who benefited from slimming injections versus those who benefited from dietary advice alone. When taking semaglutide injections once a week, as many as 86.4% of participants actually lost weight, as opposed to 31.5% of participants who lost weight only after being given advice (without injections). The following table displays the precise data:
| Weight Loss/Intervention | Weight loss injection once a week – semaglutide (e.g. Ozempic) | Nutrition education and lifestyle change (placebo) |
| Weight loss of 5% or more compared to your starting weight | 86.4% of people joining the study (1047 people from the study) | 31.5% of people joining the study (182 people) |
| Weight loss of 10% or more compared to your starting weight | 69.1% of people joining the study (838 people from the study) | 12% of people joining the study (69) |
| Weight loss of 15% or more compared to your starting weight | 50.5% (612 people from the study) | 4.9% of people joining the study (28) |
The table clearly shows that injecting semaglutide resulted in much more effective weight loss than just changing eating habits.
Works Cited
“Zastrzyki Na Odchudzanie – Ile Można Schudnąć? – Polki.pl.” Polki.pl, 24 Jan. 2023, polki.pl/dieta-i-fitness/odchudzanie,zastrzyki-na-odchudzanie-ile-mozna-schudnac-spodziewane-efekty,10448926,artykul.html.
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